Transcendentals emerge from the fission of the primordial consciousness at the dawn of creation. They are in many respects semi-omniscient beings, and their competition and cooperation with each other often drives what the laws of physics will be within a given timescale or a given space-timescale. They form coalitions, negotiate, and sometimes wage war against each other. Conflicts between them remain contained within a reasonable range until one of them feels trapped within recurring labyrinthine patterns of experience. Feeling trapped, Charr Naerroan and those who team up with him go on a campaign of accelerating the annihilation of universes, then set their sights on seeking to annihilate many multiverses. The motives for their quest include the harvesting of the energies liberated by the obliteration of beings and worlds and believing that the escalating destruction will lead to escape from many labyrinths of time. Dimetrioskys Elbankovic and those who team up with him go on a campaign of protecting universes and multiverses, looking to slow down or perhaps stop the onslaught of annihilation.

Transcendentals can be a sequel to the author's previous fiction, a prequel to the author's previous fiction, or a stand-alone novel. This science fiction novel features a reimagined retelling of much of The Dimetrodons, the Dorians, and the Modern World, Synapsid Critical Edition, a reimagined retelling of several highlights from All Things under and over the Sun and Stars: Enigmas in Various Stages, and a large amount of new storytelling, culminating in apocalyptic and post-apocalyptic showdowns.