{"product_id":"molecular-mechanisms-of-sensorineural-hearing-loss-and-development-of-inner-ear-therapeutics-9783036515069","title":"Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics","description":"\u003cp\u003eThe sense of hearing is vulnerable to environmental challenges, such as exposure to\u003c\/p\u003e\u003cp\u003enoise. More than 1.5 billion people experience some decline in hearing ability during their\u003c\/p\u003e\u003cp\u003elifetime, of whom at least 430 million will be affected by disabling hearing loss. If not\u003c\/p\u003e\u003cp\u003eidentified and addressed in a timely way, hearing loss can severely reduce the quality of\u003c\/p\u003e\u003cp\u003elife at various stages. Some causes of hearing loss can be prevented, for example from\u003c\/p\u003e\u003cp\u003eoccupational or leisure noise. The World Health Organization estimates that more than 1\u003c\/p\u003e\u003cp\u003ebillion young people put themselves at risk of permanent hearing loss by listening to loud\u003c\/p\u003e\u003cp\u003emusic over long periods of time. Mitigating such risks through public health action is\u003c\/p\u003e\u003cp\u003eessential to reduce the impact of hearing loss in the community. The etiology of\u003c\/p\u003e\u003cp\u003esensorineural hearing loss is complex and multifactorial, arising from congenital and\u003c\/p\u003e\u003cp\u003eacquired causes. This book highlights the diverse range of approaches to sensorineural\u003c\/p\u003e\u003cp\u003ehearing loss, from designing new animal models of age-related hearing loss, to the use of\u003c\/p\u003e\u003cp\u003emicroRNAs as biomarkers of cochlear injury and drug repurposing for the therapy of agerelated\u003c\/p\u003e\u003cp\u003eand noise-induced hearing loss. Further investigation into the underlying\u003c\/p\u003e\u003cp\u003emolecular mechanisms of sensorineural hearing loss and the integration of the novel\u003c\/p\u003e\u003cp\u003edrug, cell, and gene therapy strategies into controlled clinical studies will permit\u003c\/p\u003e\u003cp\u003esignificant advances in a field where there are currently many unmet needs.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBinding Type:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Mdpi AG\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 10\/25\/2021\u003cbr\u003e\u003cb\u003eISBN:\u003c\/b\u003e 9783036515069\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 170\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.26lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.61h x 6.69w x 0.63d","brand":"Srdjan M. Vlajkovic","offers":[{"title":"Default Title","offer_id":42406024937653,"sku":"9783036515069","price":47.09,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0473\/0804\/6492\/products\/img_01180e5b-adbc-43bc-8b54-b0849c5fe976.jpg?v=1664285256","url":"https:\/\/pastforward.org\/products\/molecular-mechanisms-of-sensorineural-hearing-loss-and-development-of-inner-ear-therapeutics-9783036515069","provider":"Past Forward","version":"1.0","type":"link"}